Nerve Block Manual - NYSORA

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NYSORA Books

NYSORA Nerve Block Manual

The ultimate guide to ultrasound-guided peripheral nerve blocks.

Overview

A trusted resource for performing ultrasound-guided nerve blocks with precision and consistency.
01
A definitive step-by-step guide to ultrasound-guided peripheral nerve blocks and fascial plane injections.
02
Practical, reproducible techniques immediately applicable in clinical practice. 
03
Clear descriptions of anatomy, block distribution, and procedural goals. 
04
Easy-to-follow instructions on transducer positioning, ultrasound scanning, and needle guidance.
05
Guidance on local anesthetic selection, dosing, and volume recommendations.
06
Rich illustrations and Reverse Ultrasound Anatomy visuals to improve understanding of sonoanatomy. 
01
A definitive step-by-step guide to ultrasound-guided peripheral nerve blocks and fascial plane injections.
02
Practical, reproducible techniques immediately applicable in clinical practice. 
03
Clear descriptions of anatomy, block distribution, and procedural goals. 
04
Easy-to-follow instructions on transducer positioning, ultrasound scanning, and needle guidance.
05
Guidance on local anesthetic selection, dosing, and volume recommendations.
06
Rich illustrations and Reverse Ultrasound Anatomy visuals to improve understanding of sonoanatomy. 

Discover the Nerve Block Manual

Everything you need to learn or teach veterinary regional anesthesia

Key Features

A comprehensive and highly practical guide to nerve blocks and fascial plane injections.
Step-by-step presentation of each nerve block technique.
Clear descriptions of anatomy, landmarks, and block distribution.
Practical instructions for transducer placement, ultrasound scanning, and needle approach.
Local anesthetic selection with dosing and volume recommendations.
Decision-making flowcharts to guide technique execution.
Highly didactic illustrations, including Reverse Ultrasound Anatomy visuals for intuitive sonoanatomy interpretation.

Quick facts

Each chapter starts with quick facts on indications, goals, patient positioning, and key landmarks. Setting a solid foundation for further detailed learning.

Anatomy and block distribution

Detailed functional and ultrasound anatomy with the distribution of each specific nerve block.

Technique

Comprehensive instructions on transducer positioning, ultrasound scanning techniques, needle injection paths, and local anesthetic spread. Step-by-step practical tips immediately applicable in clinical practice.

Decision-making algorithm

Recommendations for selecting the appropriate local anesthetic, including dosing and volume.

Deluxe Edition

Everything you need to learn or teach about regional anesthesia.

Nerve Block Manual Deluxe

The Deluxe Edition is a work of art and a collector’s item to be treasured by practitioners of ultrasound-guided peripheral nerve blocks and interventional analgesia injections.
  • Hardcover
  • Author’s signed copy
Nerve Block
Manual Deluxe

At the Intersection of Art and Science

Hand-Drawn Illustrations

Gallery

Take a closer look at the illustrations inside the manual.

Manual de Los Bloqueos de Nervios Periféricos

Guía definitiva para biopsias de nervios periféricos (BNP) guiadas por ecografía e inyecciones de analgesia intervencionista. Comprar ahora!

Manual Dos Bloqueios de Nervos Periféricos

Guia definitivo para bioqueios de nervos periféricos (PNBs) guiados por ultrassom e injeções de analgesia intervencionista. Comprar Agora!

Newest Updates

Newest Updates

Better together: Parasternal and rectus sheath blocks improve post-sternotomy pain and breathing

Pain after median sternotomy remains one of the most challenging aspects of cardiac anesthesia and recovery. Despite advances in surgical technique and multimodal analgesia, many patients experience moderate to severe discomfort in the early postoperative period. This pain is not merely distressing—it directly interferes with deep breathing, coughing, and mobilization, all essential components of enhanced recovery pathways. When pain limits these functions, pulmonary complications such as atelectasis and pneumonia become more likely, leading to longer mechanical ventilation and ICU stays. Regional anesthesia has become an increasingly important tool in addressing this issue, providing effective, targeted analgesia without the hemodynamic risks associated with neuraxial techniques. The ultrasound-guided parasternal (pecto-intercostal plane) block is one of the most widely adopted options for median sternotomy. By anesthetizing the anterior cutaneous branches of the intercostal nerves (T2–T6), it provides substantial relief from sternal pain and reduces opioid consumption. However, the parasternal block does not consistently cover the lower sternum and epigastric region—precisely where mediastinal and pleural drains emerge. Pain at these drain exit sites can persist even when the sternum itself is well controlled, compromising respiratory exercises and delaying extubation. The rectus sheath block (RSB), traditionally used for midline abdominal incisions, targets the anterior cutaneous branches of T6–T9 and may therefore complement the parasternal block by extending coverage to this critical epigastric zone. This study set out to determine whether combining the rectus sheath block with the parasternal block could improve pain control and respiratory recovery after cardiac surgery via median sternotomy. Study objective and methods The primary objective of the study was to determine whether parasternal and rectus sheath blocks improve pain at rest at extubation compared to parasternal and epigastric infiltration.  Design: Single-centre, single-blinded, randomized controlled superiority trial. Setting: University Hospital, Italy. Population: 58 adult patients (ASA I–IV) undergoing elective cardiac surgery via […]

Read more

PENG block or SIFICB? RCT compares dynamic pain relief in hip fracture patients

Hip fractures are among the most painful orthopedic injuries, particularly during movement or even minor positional changes before surgery. This intense pain not only compromises patient comfort but also activates the sympathetic nervous system, impacts hemodynamic stability, and complicates positioning for spinal anesthesia. Effective preoperative analgesia is therefore critical—not only to improve patient experience but also to optimize surgical conditions and reduce reliance on systemic opioids. Peripheral nerve blocks (PNBs) have become an integral part of multimodal pain management strategies for hip fractures. They lower pain scores, reduce opioid consumption, and are especially beneficial in older patients, who face heightened risks of opioid-related side effects. Current guidelines recommend fascia iliaca compartment block (FICB), with the supra-inguinal approach (SIFICB) offering broader sensory coverage than the conventional infra-inguinal technique. The SIFICB covers the femoral nerve and lateral femoral cutaneous nerve (LFCN), with spread to the obturator nerve in some cases. This broad coverage makes SIFICB effective for both hip and lateral thigh pain. More recently, the pericapsular nerve group (PENG) block has been introduced as a targeted option for hip analgesia. By blocking articular branches of the femoral, obturator, and accessory obturator nerves—responsible for innervating the anterior hip capsule—PENG aims to deliver potent pain relief while sparing quadriceps strength. This motor-sparing feature has led some clinicians to consider PENG superior to FICB, particularly in frail or elderly patients requiring early mobilization. This randomized controlled trial directly compared the efficacy of PENG and SIFICB for managing dynamic pain in patients with hip fractures, providing substantial new evidence for clinical decision-making. Study objective and methods The primary objective of this study was to evaluate whether the PENG block provides greater reduction in dynamic pain (pain during passive hip flexion) compared to the SIFICB in patients with hip fractures.  Study design Type: Prospective, single-center, randomized […]

Read more

Better together: Parasternal and rectus sheath blocks improve post-sternotomy pain and breathing

Pain after median sternotomy remains one of the most challenging aspects of cardiac anesthesia and recovery. Despite advances in surgical technique and multimodal analgesia, many patients experience moderate to severe discomfort in the early postoperative period. This pain is not merely distressing—it directly interferes with deep breathing, coughing, and mobilization, all essential components of enhanced recovery pathways. When pain limits these functions, pulmonary complications such as atelectasis and pneumonia become more likely, leading to longer mechanical ventilation and ICU stays. Regional anesthesia has become an increasingly important tool in addressing this issue, providing effective, targeted analgesia without the hemodynamic risks associated with neuraxial techniques. The ultrasound-guided parasternal (pecto-intercostal plane) block is one of the most widely adopted options for median sternotomy. By anesthetizing the anterior cutaneous branches of the intercostal nerves (T2–T6), it provides substantial relief from sternal pain and reduces opioid consumption. However, the parasternal block does not consistently cover the lower sternum and epigastric region—precisely where mediastinal and pleural drains emerge. Pain at these drain exit sites can persist even when the sternum itself is well controlled, compromising respiratory exercises and delaying extubation. The rectus sheath block (RSB), traditionally used for midline abdominal incisions, targets the anterior cutaneous branches of T6–T9 and may therefore complement the parasternal block by extending coverage to this critical epigastric zone. This study set out to determine whether combining the rectus sheath block with the parasternal block could improve pain control and respiratory recovery after cardiac surgery via median sternotomy. Study objective and methods The primary objective of the study was to determine whether parasternal and rectus sheath blocks improve pain at rest at extubation compared to parasternal and epigastric infiltration.  Design: Single-centre, single-blinded, randomized controlled superiority trial. Setting: University Hospital, Italy. Population: 58 adult patients (ASA I–IV) undergoing elective cardiac surgery via […]

Read more

PENG block or SIFICB? RCT compares dynamic pain relief in hip fracture patients

Hip fractures are among the most painful orthopedic injuries, particularly during movement or even minor positional changes before surgery. This intense pain not only compromises patient comfort but also activates the sympathetic nervous system, impacts hemodynamic stability, and complicates positioning for spinal anesthesia. Effective preoperative analgesia is therefore critical—not only to improve patient experience but also to optimize surgical conditions and reduce reliance on systemic opioids. Peripheral nerve blocks (PNBs) have become an integral part of multimodal pain management strategies for hip fractures. They lower pain scores, reduce opioid consumption, and are especially beneficial in older patients, who face heightened risks of opioid-related side effects. Current guidelines recommend fascia iliaca compartment block (FICB), with the supra-inguinal approach (SIFICB) offering broader sensory coverage than the conventional infra-inguinal technique. The SIFICB covers the femoral nerve and lateral femoral cutaneous nerve (LFCN), with spread to the obturator nerve in some cases. This broad coverage makes SIFICB effective for both hip and lateral thigh pain. More recently, the pericapsular nerve group (PENG) block has been introduced as a targeted option for hip analgesia. By blocking articular branches of the femoral, obturator, and accessory obturator nerves—responsible for innervating the anterior hip capsule—PENG aims to deliver potent pain relief while sparing quadriceps strength. This motor-sparing feature has led some clinicians to consider PENG superior to FICB, particularly in frail or elderly patients requiring early mobilization. This randomized controlled trial directly compared the efficacy of PENG and SIFICB for managing dynamic pain in patients with hip fractures, providing substantial new evidence for clinical decision-making. Study objective and methods The primary objective of this study was to evaluate whether the PENG block provides greater reduction in dynamic pain (pain during passive hip flexion) compared to the SIFICB in patients with hip fractures.  Study design Type: Prospective, single-center, randomized […]

Read more

Nerveblock Manual in Numbers

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Chapters 0
Illustrations 0 +
Reviewed by NYSORA’s International Edu Board

Why NYSORA / Trust Section

Regional anesthesia continues to evolve, and clinicians face increasing demands to master nerve block techniques with precision, safety, and efficiency. Access to high-quality, practical, and evidence-based education is essential. NYSORA's Nerve Block Manual is developed by international experts and reviewed by NYSORA’s educational board. It provides clear, step-by-step guidance, high-yield clinical tips, and detailed anatomical and ultrasound-based insights, empowering clinicians to perform nerve blocks with confidence, improve patient outcomes, and stay at the forefront of modern regional anesthesia.
Get Your Copy

Nerve Block Manual

Available in paperback and Deluxe Edition—designed to refine technique, improve success, and patient safety.

Frequently Asked Questions

Common questions about our book.

The primary difference between the Nerve Block Manual and the Nerve Block Manual Deluxe lies in their presentation and design aesthetics.

The Nerve Block Manual offers detailed, step-by-step guidance on ultrasound-guided PNBs and fascial plane injection techniques, serving as an essential resource for medical professionals aiming to master these techniques.

Conversely, the Nerve Block Manual Deluxe is not just an instructional guide—it is truly a work of art. Printed on premium paper with superior bindings, every element of its design and layout is crafted with precision, resulting in an elegant and practical collector’s item. Moreover, the Deluxe Edition boasts a robust hardcover and is housed in a custom box adorned with raised plasticized color artwork. This deluxe edition is a treasure for practitioners, combining both top-notch content with a stunning design. Adding to its exclusivity, each copy is personally signed by Prof. Dr. Admir Hadzic himself, making it an invaluable addition to any medical professional’s collection.

The Nerve Block Manual (Deluxe) is ideal for anesthesiology and pain management practitioners who perform nerve blocks and interventional analgesia injections. It is designed to assist medical professionals who are new to the field, while also serving as a valuable reference for seasoned practitioners. Therefore, the Nerve Block Manual (Deluxe) is a fundamental resource for medical professionals of all experience levels.

The Nerve Block Manual (Deluxe) provides step-by-step instructions, practical tips, detailed decision-making algorithms, and enhanced visual aids that facilitate a deeper understanding of nerve block techniques, leading to improved patient safety and satisfaction.

Absolutely. With its comprehensive content, clear instructions, and high-quality visual aids, the Nerve Block Manual (Deluxe) is an excellent resource for teaching both students and practitioners in the field of anesthesiology and pain management.

The Nerve Block Manual Deluxe can be purchased directly through NYSORA’s official shop, while the Nerve Block Manual is available on Amazon.com and Google Books.

Yes, NYSORA offers a range of online resources, YouTube videos and the Nerve Blocks App that complement the content of the Nerve Block Manual (Deluxe). There is the NYSORA Learning Management System (LMS) as well where you can join in discussions and share your experiences with your peers.

From Fundamentals to Advanced Joint Interventions with Live Demonstrations Join us at the Hong Kong Pain Conference in May 2026!

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