Perioperative vasopressor management in surgical patients

Perioperative hypotension remains one of the most critical challenges in modern anesthesia and surgical care. Maintaining adequate mean arterial pressure (MAP) is essential to ensure sufficient tissue perfusion...

Immunometabolism in perioperative medicine

Introduction A 2026 publication in BJA (British Journal of Anaesthesia), highlights a rapidly evolving concept in modern medicine: immunometabolism. This field explores how metabolic processes influence immune ...

PEEP optimization in obese patients during general anesthesia

Introduction The growing prevalence of class III obesity (BMI ≥ 40 kg/m²) is transforming perioperative care worldwide. Patients with obesity present unique respiratory and cardiovascular challenges, particular...

The role of perioperatively acquired muscle weakness in postoperative fatigue

Postoperative recovery is often associated with pain, surgical wound healing, and restoration of organ function. However, postoperative fatigue (POF) is one of the most common yet frequently overlooked complica...

Intraoperative methadone: promise and pitfalls in perioperative pain management

Introduction Intraoperative methadone has re-emerged as a topic of major interest in modern anesthesiology. Traditionally used for opioid dependence treatment and chronic pain management, methadone is now being...

S-ketamine reduces POD in elderly arthroplasty patients

A new randomized controlled trial published in Anesthesiology (2026;144:63–76) reports that perioperative S-ketamine significantly reduces postoperative delirium (POD) in older adults undergoing total hip or kn...