Postoperative nausea and vomiting (PONV) - NYSORA

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Postoperative nausea and vomiting (PONV)

Postoperative nausea and vomiting (PONV)

Learning objectives

  • Prevent and treat postoperative nausea and vomiting (PONV)

Definition 

  • Postoperative nausea and vomiting (PONV) is the second most common postoperative complication after pain

Scoring

Scoring systems like the Apfel simplified risk score can help raise awareness of PONV and thus increase prophylaxis use. The incidence of PONV, with the presence of 0, 1, 2, 3, and 4 risk factors is approximately 10%, 20%, 40%, 60%, and 80%, respectively.

Risk factorPoints
Female gender1
Non-smoker1
History of PONV and/or motion sickness1
Postoperative opioids1
Sum of points0-4

Management

postoperative nausea and vomiting, PONV management, nitrous oxide, neostigmine, regional anesthesia, opioid, antiemetic, prophylaxis, volatile, 5HT3, corticosteroids, antihistamines, dopamine, propofol, NK-1, anticholinergics, smoker, laparoscopic, bariatric, gynecological, cholecystectomy

PONV in children

  • Children have different risk factors for PONV than adults:
    • Age ≥3 years 
    • History of PONV/motion sickness 
    • Family history of PONV
    • Post-pubertal female
    • High-risk surgery (strabismus, adenotonsillectomy, otoplasty)
    • Surgery <30 minutes
    • Volatile anesthetics
  • Dexamethasone and 5HT antagonists are the antiemetics of choice in children:
    • 0 risk factors
      • No prophylaxis or dexamethasone or 5HT3 antagonist
    • 1-2 risk factors
      • Dexamethasone and 5HT3 antagonist
    • >2 risk factors 
      • Dexamethasone and 5HT3 antagonist + consider total intravenous anesthesia

Keep in mind

  • Do not underestimate the severity of PONV, patients report that it’s a worse experience than pain
  • PONV can lead to decreased patient satisfaction, aspiration, dehydration, increased length of stay and higher medical costs

Suggested reading

  • Gan TJ, Belani KG, Bergese S, et al. Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting [published correction appears in Anesth Analg. 2020 Nov;131(5):e241]. Anesth Analg. 2020;131(2):411-448.

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