Mitral stenosis - NYSORA

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Mitral stenosis

Learning objectives

  • Describe the causes and subsequent pathophysiology of mitral stenosis
  • Classify the severity of mitral stenosis
  • Anesthetic management of mitral stenosis

Definition & mechanisms

  • Mitral stenosis occurs when the mitral valve is narrowed and blood cannot flow normally
  • Causes: 
CommonRheumatic fever
Degenerative calcification
Endocarditis
UncommonInfiltrating diseases
Congenital deformities
Diseases that affect multiple systems (e.g., sarcoidosis)

Signs & symptoms

  • Patients will remain asymptomatic for many years (compensation due to the compliant left atrium dilating and keeping pulmonary venous pressures stable)
  • As the disease progresses, compensation is overcome and pulmonary hypertension develops
  • Pulmonary edema and dyspnea
  • Fatigue
  • More frequent lower respiratory tract infections
  • Atrial fibrillation will rapidly progress the pathophysiology 

Severity assessment

MildModerateSevere
Mean pressure decrease <5 mm Hg6–10 mm Hg>10 mm Hg
Pressure half-time<139 ms140–219 ms≥220 ms
Valve area1.6–2.0 cm21.5–1.0 cm2<1.0 cm2

Management

mitral stenosis, anesthetic management, dyspnea, fatigue, right heart failure, jugular venous pressure, edema, exercise tolerance, echocardiography, ECG, atrial fibrillation, warfarin, heparin, afterload, preload, sinus rhythm, nitrous oxide, hypoxia, hypercapnia, acidosis, inotropes, phosphodiesterase inhibitors, contractility, neuraxial anesthesia, hypotension

Suggested reading

  • Holmes K, Gibbison B, Vohra HA. Mitral valve and mitral valve disease. BJA Education. 2017;17(1):1-9.
  • Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63:e57.

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