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During Nerve Block Injection, avoidance of excessive resistance/pressure to injection is important in decreasing the risk of intraneural/intrafascicular injection?
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Complications Of Peripheral Nerve Blocks

There are relatively few published reports of complications associated with the use of peripheral nerve blocks. Because there is a relative paucity of published information on the mechanisms of neuronal injury after nerve blockade and methods to prevent them, some of the discussion will necessarily be theoretical.
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Sedation-Analgesia During Local and Regional Anesthesia

During local and regional anesthesia, it is a common practice to administer both sedative and analgesic medications to enhance patient comfort during the operation. Use of local anesthetic infiltration and peripheral nerve blocks (PNBs) techniques in combination with intravenous (IV) sedative-hypnotic and analgesic drugs is commonly referred to as monitored anesthesia care (MAC)....
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Diagnosis and Managment of Intraspinal, Epidural, and Peripheral Nerve Hematoma

Spinal epidural hematoma (SEH) is an accumulation of blood in the potential space between the dura and the bone. Hemorrhage into the spinal canal most commonly occurs in the epidural space because of the prominent epidural venous plexus. SEH may be spontaneous or may follow minor trauma, such as lumbar puncture or neuraxial anesthesia. It is more likely to occur in anticoagulated or thrombocytopenic patients, or in those with liver disease or alcoholism....
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Complications of Peripheral Nerve Blocks

Although there are relatively few published reports of anesthesia-related nerve injury associated with the use of peripheral nerve blocks (PNBs), it is likely that the commonly cited incidence (0.4%) of severe injury is underestimated owing to underreporting.1...
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